Carlyle is usually the first bottle my patients find: it's everywhere on Amazon, it's inexpensive, and the label promises a lot — 3,000 mg of cold-pressed pumpkin seed oil per serving, 200 softgels, non-GMO, gluten-free.

To be fair, it's a decent oil. If you are NOT on a GLP-1 and simply want an affordable DHT blocker for menopausal thinning, you could do worse.

But it's one ingredient. There is no L-Cystine in this bottle — no sulfur at all. It addresses the hormonal half of hair loss and leaves the GLP-1 half completely untouched. A patient of mine said it best: "I've been taking pumpkin seed oil for four months and I still cry every time I shower."

→ Available on Amazon. Typical price: $15–$20.

Horbäach's pitch is volume: 3,000 mg per serving at one of the lowest prices per milligram you'll find. For patients who believe a bigger dose means a better result, this bottle looks like the smart buy.

Here's what I explain in my office: DHT blocking doesn't scale that way. Once the pathway is quieted, tripling the dose doesn't triple the effect — and it certainly doesn't create sulfur out of nothing. A mega-dose of the wrong lever is still the wrong lever.

The oil itself is fine: cold-pressed, non-GMO, gluten-free. But for a woman on a GLP-1, it answers a question she isn't asking.

→ Available on Amazon. Typical price: $12–$18.

On paper, this looks like an upgrade: pumpkin seed oil AND saw palmetto, 300 softgels, clean sourcing, honest pricing. Two ingredients instead of one.

The problem is that both ingredients do the same job. Saw palmetto quiets DHT — exactly like pumpkin seed oil does. So this combination doubles down on the hormonal half of hair loss while the GLP-1 half — the sulfur your liver is pulling away from your follicles — still gets nothing. No L-Cystine here either.

I have patients who genuinely like this product, and for purely hormonal thinning it's a reasonable pick. But the women who come to me on Mounjaro or Zepbound need more than a second guard on the same door.

→ Available on Amazon. Typical price: $20–$26.

NOW is the brand my patients trust the most, and that trust is earned: they've been making no-frills, honestly-dosed supplements since 1968. Their pumpkin seed oil is exactly what it says — 1,000 mg, cold-pressed, no fillers — at a fair price.

If pumpkin seed oil alone could fix GLP-1 hair loss, this is the bottle I'd recommend.

But it can't, and that's the point. The brand isn't the problem — the category is. One patient told me: "I did everything right. I took it every morning for three months and my brush was still full." Plain pumpkin seed oil, from any brand, covers the DHT side and nothing else. It was never designed for what a GLP-1 does to your body.

→ Available on Amazon and most drugstores. Typical price: $18–$25.